GMP for the pharmaceutical manufacturing practices, is responsible for directing the drug producers, production plants, production processes, quality management, and so a set of management system to ensure drug quality. Since 1992, countries in the pharmaceutical industry since the implementation of clean production floor as a basis for the pharmaceutical industry the hardware level.
GMP requirements clean shop floor should be used overall is good, smooth, no cracking, abrasion resistance, impact resistance, easy to build up static electricity, cleaning materials, dust easily, at home and abroad many of the shop floor usually clean the whole polymer surface, which basically called "self-leveling coating" materials mainly due to general chemical substrates for the epoxy coating, so internally known as "self-leveling epoxy coating.
" This is a weak analysis of the dust of the material (low dust material analysis mainly metal, polyester surface decoration materials, paint), has good gloss, smoothness, cleanliness, hardness, currently in the country by many pharmaceutical manufacturers and users to accept and use. 1 Introduction epoxy self-leveling epoxy coating for the coating film is based on material, then by adding a curing agent, non-volatile diluents, additives and pigments and fillers made into a high-performance solvent-free paint .
Self-leveling epoxy coating film forming process is a chemical method, first soluble low molecular weight epoxy resin coating on the substrate surface, the molecules react with Er Shi to further increase the molecular weight or crosslinked to form tough film. Which required use of epoxy resin to film at room temperature, and the paint film requires a high viscosity relay, strong mechanical strength, chemical resistance and good electrical resistance.
Self-leveling epoxy floor cleaner have the following characteristics: self-leveling coating is good, a film, the construction is simple; film with tough, abrasion resistance is good, non-toxic characteristics of non-combustion; surface roughness smooth, with good decoration, cleanliness requirements to meet 100 level.
(100 class clean room required degree of air per cubic meter of dust particles greater than or equal 0 5 m number less than or equal 3500) 2 coating material properties after construction can achieve the smooth features, known as leveling, flow level of coating applications is a very important issue, it affects the apparent and the gloss coating, when the paint brush in the substrate, it will leave Shuahen, this Shuahen may, before the paint is not drying to reduce the flow of .
When the coating leveling is bad, it can be seen with the naked eye the case of the uneven surface coating. When the difference to the naked eye can not see, at this time that film is flat, smooth coating to the driving force from the grievance is not gravity, but surface tension. In theory, the lower the viscosity paint or coating thicker, the better leveling.
As the special self-leveling coating is generally required after the coating film has good leveling the same time, while keeping good surface resistance. Throughout the current self-leveling epoxy material system at home and abroad, there are two main technical guidelines, first, use an appropriate amount of solvent to achieve good leveling coating, the process of painting, paint filler will gradually decline, curing After the film has good leveling, but not high surface hardness, poor wear resistance, while the construction may have more spots on the surface flaw such as lack of, which is one-sided