The New Achievement Obtained in the DNA Backbone Sulfur-modification

The New Achievement Obtained in the DNA Backbone Sulfur-modification

It s reported by Science Times that the article DNA phosphorothioation is widespread and quantized in bacterial genomes is issued in the Proceedings of the National Academy of Sciences of the United States (PNAS). The article is jointly completed by Shanghai Jiao Tong University, Wuhan University and MIT with Wang Lianrong as the first author and Chen Shi and Peter C. Dedon as correspondence authors. The achievement denotes a major progress in the field of the DNA backbone sulfur-modification, and also another new fruit of the continuous cooperation between Deng Zixin's team and Peter C. Dedon besides the chemical nature of the DNA backbone sulfur-modification they reported last time.

Experts comment that the recent systematic progress in this field has pushed the research on the DNA backbone sulfur-modification to a new stage. Lately, the Chinese team has been invited to write the chapter Phosphorothioation: an unusual post-replicative modification on the DNA backbone in DNA Replication, an English monograph.

Full Text: DNA phosphorothioation is widespread and quantized in bacterial genomes

Translated by Wang Jie | Reviewed by Tian Cong